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Date: 8-7-2019
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Date: 1-8-2018
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Date: 2-10-2018
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Reactivity of Aziridinium Ions
As mentioned in the introduction, aziridinium ions can be obtained through intramolecular substitution of amines bearing a leaving group at the β-position or through N-functionalization of neutral aziridines. An overview will be given of both pathways and the reactivity of aziridinium ions, regardless of their origin, will be investigated theoretically.
Scheme 1: Rearrangement of β-amino alcohols via aziridinium ions
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