تسجيل الدخول

تسجيل

Anions , Borates

المؤلف:  Sue Jickells , Adam Negrusz (Editors)

المصدر:  Clarkes Analytical Forensic Toxicology

الجزء والصفحة:  111

2026-09-23

14

Anions , Borates

Boric acid has for many years been used as a common household antiseptic for external use. Sodium borate (borax) is used in cleaning agents, wood preservatives and fungicides. Compounds of boron have relatively low toxicity. However, a number of cases of acute and chronic boron poisoning have been reported in children and adults. Signs and symptoms have generally included diarrhoea and vomiting, and seizures in more severe cases.

ICP-MS has been used to measure the concentration of boron in blood and tissues in patients who receive treatment with boron-containing drugs such as boronphenylalanine (BPA) as part of boron neutron capture therapy of certain cancers (Morten and Delves 1999). Plasma boron concentrations ranging from 200 to 1600 mg/L have been reported in children in fatal cases of acute poisoning with borates. Survival has also been reported in cases of adult poisoning despite admission boron concentrations in excess of 1000 mg/L.